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Generic Name
Glibenclamide
Trade Name
Diaben
Risk Category
C
  • Studies on animals show adverse effect and toxicity on fetus.
  • No adequate and well controlled studies done on pregnant women.
  • Drugs should be given only if the potential benefit outweighs the potential risk to the fetus.
FDA Pregnancy Risk Categories

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Indication
Indication
  • Oral hypoglycemic, sulfonylurea agent.
  • Fetal Risk
    Fetal Risk
  • Not teratogenic or fetotoxic in animals.
  • No adequate human data but possible association with ear defects in 1st trimester exposure.
  • The incidence of congenital malformations, fetal and neonatal complications are increased with oral hypoglycemic agents because of poor controlling of maternal hyperglycemia.
  • Risk of neonatal hypoglycemia and intrauterine fetal death.
  • Breast Feeding
    Breast Feeding
  • Unknown excretion into milk, unknown effect on nursing infants but hypoglycemia is a potential side effect.
  • Other Trade Names
     
    The information on this Web site is not intended as a substitute for the advice and care of your doctor or other health-care provider. Always consult your doctor if you have any questions about exposures during pregnancy and lactation, and before you take any medications. Please read the Terms and Conditions before using this website.
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