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Generic Name
Cocaine
Trade Name
Cocaine
Risk Category
C*
  • Studies on animals show adverse effect and toxicity on fetus.
  • No adequate and well controlled studies done on pregnant women.
  • Drugs should be given only if the potential benefit outweighs the potential risk to the fetus.
The risk category will be X in non-medicinal use.
FDA Pregnancy Risk Categories

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Indication
Indication
  • sympathomimetic.
  • Fetal Risk
    Fetal Risk
  • Crosses human placenta.
  • It decreases uterine blood flow producing fetal hypoxemia, hypertension and tachycardia.
  • Possible association between maternal use of cocaine and preterm delivery, abortions, premature rupture of membranes (PROM) and pregnancy –induced hypertension
  • Increased incidence of abruptio placenta in pregnant cocaine users .In utero exposure to cocaine causes growth retardation, fetal distress, cerebrovascular accidents (cerebral hemorrhagic infarctions) and congenital anomalies (ileal atresia, genitourinary malformations, cardiac anomalies, necrotizing enterocolitis and intestinal defects, limb reduction defects and facial defects)
  • Newborns exposed in utero to cocaine may develop neuro behavior impairment, gastrointestinal disturbances and withdrawal symptoms in the neonatal period.
  • Cocaine use in pregnancy is associated with high incidence of perinatal mortality (intrauterine and neonatal deaths), increased risk of sudden infant death syndrome (SIDS) and increased neonatal hospitalization.
  • Breast Feeding
    Breast Feeding
  • Excreted into milk. contraindicated in breast-feeding.
  • Causes irritability, tremulousness, seizures, vomiting and diarrhea in exposed infants.
  • Other Trade Names
     
    The information on this Web site is not intended as a substitute for the advice and care of your doctor or other health-care provider. Always consult your doctor if you have any questions about exposures during pregnancy and lactation, and before you take any medications. Please read the Terms and Conditions before using this website.
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