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Generic Name
Colchicine
Trade Name
Colchicine
Risk Category
C
  • Studies on animals show adverse effect and toxicity on fetus.
  • No adequate and well controlled studies done on pregnant women.
  • Drugs should be given only if the potential benefit outweighs the potential risk to the fetus.
FDA Pregnancy Risk Categories

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Indication
Indication
  • For treatment of gout and familial Mediterranean fever.
  • Fetal Risk
    Fetal Risk
  • teratogenic, embryocidal and mutagenic in some animals.
  • limited human data but no congenital malformations reported with maternal use throughout pregnancy.
  • Possible mutagenic effect of colchicine in treated men resulting in diploid spermatozoa that caused triploid children (e.g. down’s syndrome).
  • Men treated with colcichine or its derivative demecolcine may have azoospermia as a result of testicular toxicity
  • Breast Feeding
    Breast Feeding
  • Excreted into milk.
  • Safe in breast feeding.
  • Other Trade Names
     
    The information on this Web site is not intended as a substitute for the advice and care of your doctor or other health-care provider. Always consult your doctor if you have any questions about exposures during pregnancy and lactation, and before you take any medications. Please read the Terms and Conditions before using this website.
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