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Generic Name
Prochlorperazine
Trade Name
Nu-Prochlor
Risk Category
C
  • Studies on animals show adverse effect and toxicity on fetus.
  • No adequate and well controlled studies done on pregnant women.
  • Drugs should be given only if the potential benefit outweighs the potential risk to the fetus.
FDA Pregnancy Risk Categories

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Indication
Indication
  • Piperazine phenothiazine antiemetic.
  • Tranquilizer
  • Fetal Risk
    Fetal Risk
  • In animal it causes cleft palate is a split in roof of the mouth, due to failure of two sides to fuse during embryonic development. Could also be a cleft lip, which is a split in the lip">cleft palate, anencephaly, behavioral changes, decrease in postnatal weight and increased fetal mortality.
  • Crosses human placenta.
  • Isolated reports of congenital anomalies in infants exposed in utero to the drug such as cleft palate is a split in roof of the mouth, due to failure of two sides to fuse during embryonic development. Could also be a cleft lip, which is a split in the lip">cleft palate, micrognathia heart defects, skeletal defects, but majority of reports considered it safe for the fetus at maternal low doses
  • Breast Feeding
    Breast Feeding
  • Unknown excretion into milk.
  • May cause sedation in nursing infants.
  • Other Trade Names
     
    The information on this Web site is not intended as a substitute for the advice and care of your doctor or other health-care provider. Always consult your doctor if you have any questions about exposures during pregnancy and lactation, and before you take any medications. Please read the Terms and Conditions before using this website.
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