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Generic Name
Theophylline
Trade Name
Lasma
Manufacturer
Pharmax
Risk Category
C
  • Studies on animals show adverse effect and toxicity on fetus.
  • No adequate and well controlled studies done on pregnant women.
  • Drugs should be given only if the potential benefit outweighs the potential risk to the fetus.
FDA Pregnancy Risk Categories

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Indication
Indication
  • bronchodilator for treatment of asthma and obstructive pulmonary disease.
  • Fetal Risk
    Fetal Risk
  • Crosses human placenta.
  • No adequate human data but suggested possible association with cardiovascular defects, oral clefts and spina bifida in 1st trimester exposure.
  • Can cause neonatal tachycardia, vomiting, irritability if exposure was near term or with high doses.
  • Possibly decreases the incidence of preeclampsia in treated asthmatic women.
  • Doubtful association with chromosomal damage and breakage in infants exposed in utero.
  • neonatal withdrawal symptoms occur with prolonged use during pregnancy.
  • Breast Feeding
    Breast Feeding
  • Excreted into milk.
  • May cause irritability in nursing infants.
  • Compatible with breast feeding.
  • Other Trade Names
     
    The information on this Web site is not intended as a substitute for the advice and care of your doctor or other health-care provider. Always consult your doctor if you have any questions about exposures during pregnancy and lactation, and before you take any medications. Please read the Terms and Conditions before using this website.
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