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Generic Name
Melphalan
Trade Name
Alkeran
Manufacturer
Wellcome
Risk Category
D
  • Positive evidence of human fetal risk exists.
  • Potential benefits may warrant use of the drug in pregnant women despite potential risks (e.g. life threatening situations or serious illness).
FDA Pregnancy Risk Categories

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Indication
Indication
  • antineoplastic.
  • Fetal Risk
    Fetal Risk
  • Melphalan has mutagenic, and carcinogenic effects but not reported in infants exposed in utero to the drug.
  • No adequate human data but antineoplastic drugs in general can cause intrauterine growth retardation and low birth weight.
  • Occupational exposure of pregnant women to antineoplastic drugs carries risk, to the fetus including fetal loss and malformations.
  • Breast Feeding
    Breast Feeding
  • It is not known if it’s excreted in breast milk or not.
  • Use in nursing mothers insn’t recommended because of the risk of mutagenicity and carcinogenicity.
  • Other Trade Names
     
    The information on this Web site is not intended as a substitute for the advice and care of your doctor or other health-care provider. Always consult your doctor if you have any questions about exposures during pregnancy and lactation, and before you take any medications. Please read the Terms and Conditions before using this website.
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