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Generic Name
Chloramphenical and Prednisolone
Trade Name
Chloramsone
Risk Category
C*
  • Studies on animals show adverse effect and toxicity on fetus.
  • No adequate and well controlled studies done on pregnant women.
  • Drugs should be given only if the potential benefit outweighs the potential risk to the fetus.
The risk category is B for prednisolone.
FDA Pregnancy Risk Categories

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Indication
Indication
  • topical treatment of ocular infections.
  • Fetal Risk
    Fetal Risk
  • No adequate data for chloramphenicol but when used near term systemically it caused neonatal cardiovascular collapse (gray syndrome).
  • No data for topical use of the drug.
  • No well - controlled data for prednisolone but increased incidence of congenital anomalies neonatal cataract, increased incidence of stillbirths have been reported.
  • No data for topical use of the drug.
  • Breast Feeding
    Breast Feeding
  • prednisolone is safe in breast feeding.
  • Chloramphemicol is excreted into milk potential problem for nursing infant is bone marrow suppression.
  • No data for topical use of the drug.
  • Other Trade Names
     
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