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Generic Name
Dextromethorphan, Phenylpropanolamine and Glyceryl guaiacolate
Trade Name
dextromethorphan, phenyl propanolamine and glycery
Risk Category
C
  • Studies on animals show adverse effect and toxicity on fetus.
  • No adequate and well controlled studies done on pregnant women.
  • Drugs should be given only if the potential benefit outweighs the potential risk to the fetus.
FDA Pregnancy Risk Categories

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Indication
Indication
  • antitussive decongestant.
  • Fetal Risk
    Fetal Risk
  • No animal data for dextromethorphan.
  • limited human data but reported to be safe in pregnancy.
  • No adequate human data for glyceryl gualcolate (guaifenesin), but suggested possible association with inguinal hernia in 1st trimester, no fetal harm has been reported in the last two trimesters' exposure.
  • Limited human data for phenyl propanolamine but as sympathomimetic agent reported to be teratogenic producing eye and ear defects, hypospadias, polydactyly, cataract and pectus excavatum in 1st trimester exposure and with congenital dislocation of the hip when used any time in pregnancy. It also may cause constriction of uterine vessels with subsequent fetal hypoxia and bradycardia.
  • Breast Feeding
    Breast Feeding
  • No data available.
  • Other Trade Names
     
    The information on this Web site is not intended as a substitute for the advice and care of your doctor or other health-care provider. Always consult your doctor if you have any questions about exposures during pregnancy and lactation, and before you take any medications. Please read the Terms and Conditions before using this website.
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