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Generic Name
Piperazine citrate, hydrate
Trade Name
Dr. Ronwing worm Elixir
Risk Category
B
  • Controlled studies done on animals in reproduction do not indicate risk to the fetus.
  • No adequate and well-controlled studies done on pregnant women.
FDA Pregnancy Risk Categories

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Indication
Indication
  • Antihelminthic for treatment of ascariasis and enterobiasis.
  • Fetal Risk
    Fetal Risk
  • Not teratogenic in animals.
  • Limited human data.
  • Reported two cases of congenital malformations when the drug used early in pregnancy,one infant with cleft palate is a split in roof of the mouth, due to failure of two sides to fuse during embryonic development. Could also be a cleft lip, which is a split in the lip">cleft lip, cleft palate is a split in roof of the mouth, due to failure of two sides to fuse during embryonic development. Could also be a cleft lip, which is a split in the lip">cleft palate and anophthalmia and one with defect on the right foot.
  • Oral piperazine undergoes biotransformation to carcinogenic nitrosamine derivative so it is only recommended if potential maternal benefit outweighs any fetal risk or when alternative agents are not available.
  • Breast Feeding
    Breast Feeding
  • Excreted into milk.
  • No adverse effects in nursing infants have been reported but recommended to stop breast feeding 8 hours after drug ingestion.
  • Other Trade Names
     
    The information on this Web site is not intended as a substitute for the advice and care of your doctor or other health-care provider. Always consult your doctor if you have any questions about exposures during pregnancy and lactation, and before you take any medications. Please read the Terms and Conditions before using this website.
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