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Generic Name
Isopropamide iodide, cinnarizine and ephedrine hydrochloride
Trade Name
Risk Category
  • Studies on animals show adverse effect and toxicity on fetus.
  • No adequate and well controlled studies done on pregnant women.
  • Drugs should be given only if the potential benefit outweighs the potential risk to the fetus.
FDA Pregnancy Risk Categories

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  • antihistamine, decongestant.
  • Fetal Risk
    Fetal Risk
  • No adequate data for Isopropamide in pregnancy, no association with congenital anomalies has been reported although parasympatholytic agents in general may cause minor malformations.
  • Ephedrine is teratogenic in animals. No adequate human data for sympathomimetic drugs in general, but there has been reported association with minor congenital anomalies, inguinal hernia and clubfoot if used in 1st trimester.
  • No data available for cinnarizine but use of antihistamines in the last two weeks of pregnancy may cause retrolental fibroplasia in premature infants.
  • Breast Feeding
    Breast Feeding
  • Ephedrine considered safe in breast feeding, reported single case of irritability and poor sleeping in nursing infant.
  • No data for Isopropamide and cinnarizine.
  • Other Trade Names
    The information on this Web site is not intended as a substitute for the advice and care of your doctor or other health-care provider. Always consult your doctor if you have any questions about exposures during pregnancy and lactation, and before you take any medications. Please read the Terms and Conditions before using this website.
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