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Generic Name
Levonorgestrel and Ethinylestrodiol
Trade Name
Risk Category
  • Positive evidence of human fetal risk exists.
  • Potential benefits may warrant use of the drug in pregnant women despite potential risks (e.g. life threatening situations or serious illness).
  • Studies in animals and/or humans have demonstrated fetal abnormalities.
  • Fetal risk involved in use of drug, clearly outweighs potential benefit.
  • Contraindicated in women who are or may become pregnant. Don’t use.
FDA Pregnancy Risk Categories

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  • Oral contraceptive.
  • Fetal Risk
    Fetal Risk
  • Suggested possible association with multiple congenital anomalies (vactrel syndrome) when oral contraception used in pregnancy.
  • Exposure to estrogens in general in 1st trimester has been reported to cause ear, eye, cardiovascular defects and down’s syndrome.
  • 1st trimester exposure to progestational agents reported to cause cardiovascular defects and hypospadias.
  • No adequate data for Levonorgestrel.
  • Use of oral contraceptive agent before or after conception can cause neonatal hyperbilirubinemia.
  • Breast Feeding
    Breast Feeding
  • Excreted into milk.
  • Safe in breast feeding although Ethinylestradiol decreases milk production.
  • Other Trade Names
    The information on this Web site is not intended as a substitute for the advice and care of your doctor or other health-care provider. Always consult your doctor if you have any questions about exposures during pregnancy and lactation, and before you take any medications. Please read the Terms and Conditions before using this website.
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