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Generic Name
Fentanyl and Droperidol
Trade Name
Thalamonal
Manufacturer
Janssen
Risk Category
C*
  • Studies on animals show adverse effect and toxicity on fetus.
  • No adequate and well controlled studies done on pregnant women.
  • Drugs should be given only if the potential benefit outweighs the potential risk to the fetus.
The risk category is B for Fentanyl.
The risk category will be D for fentanyl if used for prolonged period or in high doses at term.
FDA Pregnancy Risk Categories

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Indication
Indication
  • narcotic analgesic.
  • Fetal Risk
    Fetal Risk
  • Fentanyl can cause loss of fetal heart rate variability without hypoxia and if used via epidural infusion it can cause neonatal respiratory depression.
  • Droperidol is not teratogenic in animals but may increase the neonatal mortality rate.
  • It crosses human placenta.
  • Inadequate human data but suggested possible association with fetal hypoplasia of righ cerebral hemisphere if used in 1st trimester.
  • Used in labor and cesarean section without maternal and neonatal complications.
  • Breast Feeding
    Breast Feeding
  • Excreted into milk, safe in breast feeding.
  • No data for droperidol.
  • Other Trade Names
     
    The information on this Web site is not intended as a substitute for the advice and care of your doctor or other health-care provider. Always consult your doctor if you have any questions about exposures during pregnancy and lactation, and before you take any medications. Please read the Terms and Conditions before using this website.
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