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Generic Name
Co-trimoxazole
Trade Name
Bactrim
Manufacturer
Roche
Drug Image
Bactrim
Risk Category
C
  • Studies on animals show adverse effect and toxicity on fetus.
  • No adequate and well controlled studies done on pregnant women.
  • Drugs should be given only if the potential benefit outweighs the potential risk to the fetus.
FDA Pregnancy Risk Categories

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Indication
Indication
  • anti-infective containing trimethoprim and sulfamethoxazole.
  • Fetal Risk
    Fetal Risk
  • Both agents cross-the placenta.
  • Theoretical possibility that trimethoprim will cause folic acid deficiency in the fetus causing congenital anomalies.
  • Should be avoided especially in 3rd trimester because of possibility of kernicterus in the neonate.
  • See Sulphonamides.
  • See trimethoprim.
  • Breast Feeding
    Breast Feeding
  • Excreted into milk in low concentrations.
  • Exposure should be avoided in premature infants, infants with hyperbilirubinemia or glucose-6-phosphate dehydrogenase deficiency.
  • May cause diarrhea and skin rash in exposed infants.
  • Other Trade Names
     
    The information on this Web site is not intended as a substitute for the advice and care of your doctor or other health-care provider. Always consult your doctor if you have any questions about exposures during pregnancy and lactation, and before you take any medications. Please read the Terms and Conditions before using this website.
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