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Generic Name
Propantheline and Chlordiazepoxide
Trade Name
Risk Category
  • Positive evidence of human fetal risk exists.
  • Potential benefits may warrant use of the drug in pregnant women despite potential risks (e.g. life threatening situations or serious illness).
The risk category is C for Propantheline.
FDA Pregnancy Risk Categories

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  • Antispasmodic (parasympatholytic).
  • Sedative.
  • Fetal Risk
    Fetal Risk
  • Use of parasympatholytic agents in human pregnancy has been reported to cause minor congenital anomalies.
  • No adequate data for propantheline, but no association with congenital malformations has been reported in 1st trimester exposure.
  • No adequate human data for chlordiazepoxide, suggested possible association with congenital malformations (microcephaly duodenal atresia, meckels diverticulum and deafness), growth and mental retardation, increased fetal death rate.
  • Chronic maternal use causes neonatal withdrawal.
  • If used in labor it causes hypotonia, hypothermia and poor feeding in the newborn.
  • Breast Feeding
    Breast Feeding
  • No data available for propantheline.
  • No data available for chlordiazepoxide, should be avoided.
  • Other Trade Names
    The information on this Web site is not intended as a substitute for the advice and care of your doctor or other health-care provider. Always consult your doctor if you have any questions about exposures during pregnancy and lactation, and before you take any medications. Please read the Terms and Conditions before using this website.
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