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Generic Name
Atovaquone and proguanil
Trade Name
Malarone
Risk Category
C
  • Studies on animals show adverse effect and toxicity on fetus.
  • No adequate and well controlled studies done on pregnant women.
  • Drugs should be given only if the potential benefit outweighs the potential risk to the fetus.
FDA Pregnancy Risk Categories

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Indication
Indication
  • Anti-protozoal for treatment of malaria.
  • Fetal Risk
    Fetal Risk
  • Atrovaquone is not teratogenic in animals.
  • Maternal toxic doses resulted in decreased fetal weight and increased fetal resorption.
  • Both agents are not teratogenic in animals.
  • No well controlled human data, recommended only for use by pregnant women traveling to malaria-endemic areas.
  • Breast Feeding
    Breast Feeding
  • Proguanil is excreted into milk in low concentration.
  • Atrovaquone is excreted into milk of lactating animals,unknown excretion into human milk.
  • Should be used with caution during breast feeding.
  • Other Trade Names
     
    The information on this Web site is not intended as a substitute for the advice and care of your doctor or other health-care provider. Always consult your doctor if you have any questions about exposures during pregnancy and lactation, and before you take any medications. Please read the Terms and Conditions before using this website.
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