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Generic Name
Zidovudine (AZT)
Trade Name
Apo-Zidovudine
Risk Category
C
  • Studies on animals show adverse effect and toxicity on fetus.
  • No adequate and well controlled studies done on pregnant women.
  • Drugs should be given only if the potential benefit outweighs the potential risk to the fetus.
FDA Pregnancy Risk Categories

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Indication
Indication
  • A systemic antiviral combination for treatment of hiv infection.
  • Fetal Risk
    Fetal Risk
  • teratogenic and fetotoxic in animals at high doses causing skeletal and developmental malformations and increased fetal loss.
  • Zidovudine crosses human placenta.
  • Limited human data: no association with cogenital anomalies has been reported, but fetal anemia and growth retardation resulted from maternal ingestion of the drug during the last two trimesters.
  • Breast Feeding
    Breast Feeding
  • Excreted into milk in sufficient amounts that may protect maternal-infant hiv transmission.
  • Limited data available as breast feeding in hiv infected patients is not recommended.
  • Other Trade Names
     
    The information on this Web site is not intended as a substitute for the advice and care of your doctor or other health-care provider. Always consult your doctor if you have any questions about exposures during pregnancy and lactation, and before you take any medications. Please read the Terms and Conditions before using this website.
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