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Generic Name
Benazepril hydrochloride (hydrochloride and hydrochlorothiazide)
Trade Name
Cibadrex
Manufacturer
Novartis Pharma
Risk Category
D
  • Positive evidence of human fetal risk exists.
  • Potential benefits may warrant use of the drug in pregnant women despite potential risks (e.g. life threatening situations or serious illness).
FDA Pregnancy Risk Categories

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Indication
Indication
  • Antihypertensive.
  • Angiotensin-converting enzyme (ACE) inhibitor.
  • Thiazide diuretic.
  • Fetal Risk
    Fetal Risk
  • maternal use of (ACE) inhibitors in general during the 2nd and 3rd trimesters is associated with renal and skull defects (hypocalvaria), oligohydramnios and intrauterine death.
  • No human data available yet for benazepril in pregnancy.
  • Breast Feeding
    Breast Feeding
  • No data available for benazepril but other ACE-inhibitors are excreted into milk in low concentrations without adverse effects on nursing infants.
  • Hydrochlorothiazide is excreted into milk, safe in breast feeding although it may suppress lactation and potential to cause thrombocytopenia in nursing infants.
  • Other Trade Names
     
    The information on this Web site is not intended as a substitute for the advice and care of your doctor or other health-care provider. Always consult your doctor if you have any questions about exposures during pregnancy and lactation, and before you take any medications. Please read the Terms and Conditions before using this website.
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