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Generic Name
Ibuprofen and Chlorzoxazone
Trade Name
Eva pharma
Risk Category
  • Controlled studies done on animals in reproduction do not indicate risk to the fetus.
  • No adequate and well-controlled studies done on pregnant women.
The risk catgory for Ibuprofen is D if used in 3rd trimester.
The risk category for Chlorzoxazone is C.
FDA Pregnancy Risk Categories

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  • Analgesic.
  • Muscle relaxant.
  • Fetal Risk
    Fetal Risk
  • No animal data for Chlorzoxazone.
  • Limited human data, no association with congenital anomalies in 1st trimester exposure has been reported.
  • No adequate human data for Ibuprofen in 1st trimester exposure but reported doubtful association with some congenital anomalies (anencephaly, cerebral palsy, microphthalmia, nasal cleft and tooth staining) and fetal death.
  • Use of the drug in 3rd trimester causes contriction of pulmonary artery to aorta">ductus arteriosus with subsequent neonatal pulmonary hypertension and oligohydramnios by affecting fetal renal function.
  • Breast Feeding
    Breast Feeding
  • No data available for Chlorzoxazone.
  • Ibuprofen is safe in breast feeding as minimal amounts is excreted into milk.
  • Other Trade Names
    The information on this Web site is not intended as a substitute for the advice and care of your doctor or other health-care provider. Always consult your doctor if you have any questions about exposures during pregnancy and lactation, and before you take any medications. Please read the Terms and Conditions before using this website.
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