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Generic Name
Cyclizine hydrochoride and Vitamin B6
Trade Name
Emetrex
Manufacturer
Amoun
Risk Category
C*
  • Studies on animals show adverse effect and toxicity on fetus.
  • No adequate and well controlled studies done on pregnant women.
  • Drugs should be given only if the potential benefit outweighs the potential risk to the fetus.
The risk category is B for Cyclizine.
FDA Pregnancy Risk Categories

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Indication
Indication
  • antiemetic antihistamine with B-complex vitamin.
  • Fetal Risk
    Fetal Risk
  • Cyclizine is teratogenic in animals but not reported in human studies. Exposure to antihistamines in general during the last two weeks of pregnancy may cause retrolental fibroplasia in premature infants.
  • The dose of vitamin B6 is above the recommended dietary allowance (rda) in pregnancy.
  • No well- controlled human data but suggested possible association between high doses of vitamin B6 and phocomelia and infantile convulsions.
  • Breast Feeding
    Breast Feeding
  • No data available for cyclizine in breast feeding.
  • Vitamin B6 is excreted into milk, safe in breast feeding although high doses may suppress lactation.
  • Other Trade Names
     
    The information on this Web site is not intended as a substitute for the advice and care of your doctor or other health-care provider. Always consult your doctor if you have any questions about exposures during pregnancy and lactation, and before you take any medications. Please read the Terms and Conditions before using this website.
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