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Generic Name
Fluorouracil
Trade Name
Adrucil
Risk Category
D
  • Positive evidence of human fetal risk exists.
  • Potential benefits may warrant use of the drug in pregnant women despite potential risks (e.g. life threatening situations or serious illness).
FDA Pregnancy Risk Categories

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Indication
Indication
  • A systemic antineoplastic agent.
  • Fetal Risk
    Fetal Risk
  • No adequate human data but suggested possible association between systemic use of the drug in first trimester and multiple congenital anomalies including: limb, digtal, vascular, gastrointestinal, urinary defects and single umbilical artery.
  • No data for topical use of the drug.
  • Reported neonatal toxic effects when the drug is used in third trimester including cyanosis and jerking extremities.
  • Occupational exposure of pregnant women to antineoplastic drugs carries risk to the fetus including fetal loss and malformations.
  • Breast Feeding
    Breast Feeding
  • Unknown excretion into human breast milk.
  • Other Trade Names
     
    The information on this Web site is not intended as a substitute for the advice and care of your doctor or other health-care provider. Always consult your doctor if you have any questions about exposures during pregnancy and lactation, and before you take any medications. Please read the Terms and Conditions before using this website.
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