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Generic Name
Carbinoxamine maleate, Dextromethorphan and Phenylephrine HCl
Trade Name
Risk Category
  • Studies on animals show adverse effect and toxicity on fetus.
  • No adequate and well controlled studies done on pregnant women.
  • Drugs should be given only if the potential benefit outweighs the potential risk to the fetus.
FDA Pregnancy Risk Categories

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  • nasal decongestant.
  • Fetal Risk
    Fetal Risk
  • No animal or human studies for carbinoxamine in pregnancy.
  • Phenylephrine is teratogenic in some animals, no well-controlled human data but suggested possible association with eye, ear and digital defects, as well as clubfoot during 1st trimester exposure and with musculoskeletal defects and umbilical hernia during exposure anytime in pregnancy.
  • It may cause uterine vessel spasm and potentiate the effects of oxytocic drugs on the uterus resulting in fetal hypoxia and bradycardia.
  • Limited data for Dextromethorphan but considered to be safe in pregnancy.
  • No animal studies.
  • Breast Feeding
    Breast Feeding
  • No data available for all agents in breast feeding.
  • Other Trade Names
    The information on this Web site is not intended as a substitute for the advice and care of your doctor or other health-care provider. Always consult your doctor if you have any questions about exposures during pregnancy and lactation, and before you take any medications. Please read the Terms and Conditions before using this website.
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