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Generic Name
Spiramycin and Metronidazole
Trade Name
Rodogyl
Risk Category
C*
  • Studies on animals show adverse effect and toxicity on fetus.
  • No adequate and well controlled studies done on pregnant women.
  • Drugs should be given only if the potential benefit outweighs the potential risk to the fetus.
The risk category is B For Metronidazole.
FDA Pregnancy Risk Categories

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Indication
Indication
  • A combination of two antibiotics with wide spectrum of efficacy.
  • Fetal Risk
    Fetal Risk
  • Crosses placenta.
  • Possible association with congenital defects if used in the first trimester as mental retardation, hip dislocation, hydrocele, cleft lip and palate, optic atrophy and had defects.
  • Breast Feeding
    Breast Feeding
  • Possible cause of diarrhea and secondary lactose intolerance in nursing infants.
  • If the stat dose of 2 gm, is used, breast feeding can be delayed for 12-24 hrs.
  • Other Trade Names
     
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