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Generic Name
Butalbital, Acetaminophen (paracetamol), Caffeine and Codeine
Trade Name
Fioricet with Codeine
Risk Category
  • Studies on animals show adverse effect and toxicity on fetus.
  • No adequate and well controlled studies done on pregnant women.
  • Drugs should be given only if the potential benefit outweighs the potential risk to the fetus.
FDA Pregnancy Risk Categories

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  • analgesic, antipyretic and antitussive.
  • Fetal Risk
    Fetal Risk
  • Crosses the placenta.
  • Inadequate human or animal studies.
  • Suggested increase in fetal abnormalities and brain tumors if used prenatally.
  • Use late in third trimester is associated with increased risk of respiratory depression.
  • Use of caffeine in the first trimester may cause birth defects and fetal arrhythmias.
  • Breast Feeding
    Breast Feeding
  • Excreted in human breast milk.
  • May cause cns depression in nursing infants.
  • Other Trade Names
    The information on this Web site is not intended as a substitute for the advice and care of your doctor or other health-care provider. Always consult your doctor if you have any questions about exposures during pregnancy and lactation, and before you take any medications. Please read the Terms and Conditions before using this website.
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