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Generic Name
Efavirenz
Trade Name
Sustiva
Risk Category
D
  • Positive evidence of human fetal risk exists.
  • Potential benefits may warrant use of the drug in pregnant women despite potential risks (e.g. life threatening situations or serious illness).
FDA Pregnancy Risk Categories

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Indication
Indication
  • A systemic antiviral agent used for treatment of hiv.
  • Fetal Risk
    Fetal Risk
  • Should be avoided in pregnant women due to its teratogenic effects in animals.
  • In animal studies, it crosses placenta, causes increased incidence of fetal resorptions, and teratogenic effects as anencephaly, anophthalmia, microphthalmia and clift palate.
  • Breast Feeding
    Breast Feeding
  • Unknown excretion into human breast milk
  • Breast feeding is not recommended with treatment.
  • Mothers are advised not to nurse their children for the risk of postnatal transmission.
  • Other Trade Names
     
    The information on this Web site is not intended as a substitute for the advice and care of your doctor or other health-care provider. Always consult your doctor if you have any questions about exposures during pregnancy and lactation, and before you take any medications. Please read the Terms and Conditions before using this website.
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