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Generic Name
Trade Name
Risk Category
  • Positive evidence of human fetal risk exists.
  • Potential benefits may warrant use of the drug in pregnant women despite potential risks (e.g. life threatening situations or serious illness).
The risk category is C in the first trimester.
FDA Pregnancy Risk Categories

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  • Angiotensin-1-converting enzyme inhibitor, antihypertensive.
  • Fetal Risk
    Fetal Risk
  • In animals it causes fetal growth retardation and incomplete bone ossification.
  • No adequate human data in first trimester but suggested possible association with cardiovascular defects and polydactyly.
  • Use in 2nd and 3rd trimester is teratogenic and toxic leading to: intrauterine growth retardation, oligohydramnios leading to skull deformities, lung hypoplasia, limb contractures, prematurity, fetal distress, neonatal anuria, renal failure requiring dialysis, neonatal hypotension, renal tubular dysplasia.
  • Breast Feeding
    Breast Feeding
  • Compatible with breast feeding as the amount excreted into milk is not significant.
  • Other Trade Names
    The information on this Web site is not intended as a substitute for the advice and care of your doctor or other health-care provider. Always consult your doctor if you have any questions about exposures during pregnancy and lactation, and before you take any medications. Please read the Terms and Conditions before using this website.
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