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Generic Name
Estradiol and Norethindrone
Trade Name
Activella
Risk Category
X
  • Positive evidence of human fetal risk exists.
  • Potential benefits may warrant use of the drug in pregnant women despite potential risks (e.g. life threatening situations or serious illness).
  • Studies in animals and/or humans have demonstrated fetal abnormalities.
  • Fetal risk involved in use of drug, clearly outweighs potential benefit.
  • Contraindicated in women who are or may become pregnant. Don’t use.
FDA Pregnancy Risk Categories

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Indication
Indication
  • A systemic hormonal combination used for treatment of menopause-associated vasomotor symptoms, genital tract atrophy, and prophylaxis of osteoporosis.
  • Fetal Risk
    Fetal Risk
  • Estrogens & Progestins’ combinations should be avoided during pregnancy & risk – benefit must be considered before its use.
  • Breast Feeding
    Breast Feeding
  • Both are excreted into human breast milk.
  • Estrogens may inhibit lactation or affect negatively the quantity & quality of Breast milk.
  • Other effects are not determined.
  • Other Trade Names
     
    The information on this Web site is not intended as a substitute for the advice and care of your doctor or other health-care provider. Always consult your doctor if you have any questions about exposures during pregnancy and lactation, and before you take any medications. Please read the Terms and Conditions before using this website.
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