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Generic Name
Lamotrigine (LTG)
Trade Name
Risk Category
  • Studies on animals show adverse effect and toxicity on fetus.
  • No adequate and well controlled studies done on pregnant women.
  • Drugs should be given only if the potential benefit outweighs the potential risk to the fetus.
FDA Pregnancy Risk Categories

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  • Anticonvulsant.
  • Fetal Risk
    Fetal Risk
  • Not teratogenic in animals but may cause intrauterine growth retardation, fetal or neonatal death, delayed ossification.
  • Crosses human placenta.
  • No well controlled human data but suggested possible association with congenital anomalies in first trimester exposure including: neural tube defects, craniofacial, limb, cardiovascular, pulmonary, bone and digital defects.
  • Reported adverse neonatal effects of lamotrigine exposure in uetro including: respiratory depression, growth retardation, septicemia, volvulus of ileum and NTD (neural tube defects).
  • Breast Feeding
    Breast Feeding
  • Excreted into milk.
  • No human data but not recommended during breast feeding.
  • Other Trade Names
    The information on this Web site is not intended as a substitute for the advice and care of your doctor or other health-care provider. Always consult your doctor if you have any questions about exposures during pregnancy and lactation, and before you take any medications. Please read the Terms and Conditions before using this website.
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