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Generic Name
Metronidazole
Trade Name
Supplin
Manufacturer
Biochemie
Risk Category
B
  • Controlled studies done on animals in reproduction do not indicate risk to the fetus.
  • No adequate and well-controlled studies done on pregnant women.
FDA Pregnancy Risk Categories

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Indication
Indication
  • anti-infective, and amebicide.
  • Fetal Risk
    Fetal Risk
  • Crosses human placenta.
  • In animals mutagenic and carcinogenic.
  • To date no association with human cancer.
  • Use in 1st trimester is controversial, possible association with congenital defects (Mental retardation, dislocated hip, hydrocele, cleft lip and palate, holotelencephaly, optic atrophy, hand defects, metatarsus varus).
  • Contraindicated in 1st trimester, acceptable in 2nd and 3rd trimesters if alternatives failed.
  • Breast Feeding
    Breast Feeding
  • Excreted into milk.
  • Possible cause of diarrhea and secondary lactose intolerance in exposed infants.
  • Should be used with caution because of potential mutagenic and carcinogenic effects.
  • With single dose (2 grams) lactation can be allowed after 12-24 hours.
  • Other Trade Names
     
    The information on this Web site is not intended as a substitute for the advice and care of your doctor or other health-care provider. Always consult your doctor if you have any questions about exposures during pregnancy and lactation, and before you take any medications. Please read the Terms and Conditions before using this website.
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