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Generic Name
Diethylamine salicylate
Trade Name
Rheumasal
Manufacturer
UPM
Risk Category
D*
  • Positive evidence of human fetal risk exists.
  • Potential benefits may warrant use of the drug in pregnant women despite potential risks (e.g. life threatening situations or serious illness).
The risk category is C in first and second trimester.
FDA Pregnancy Risk Categories

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Indication
Indication
  • topical anti-inflammatory and analgesic.
  • Fetal Risk
    Fetal Risk
  • Full dose systemic salicylate use near term are associated with prolonged labor, increased maternal blood loss during delivery, neonatal bleeding complications and jaundice.
  • Continuous large doses of salicylate are associated with decreased birth weight, increased incidence of stillbirths, premature closure of ductus arteriosus and intracranial hemorrhage.
  • These complications were not seen with low-dose salicylate.
  • Chronic salicylate intoxication (salicylism) manifested as: headache, dizziness, tinnitus, blurred vision, nausea, vomiting, tremor, convulsions, encephalopathy, and hyperventilation.
  • No data with topical salicylate.
  • Breast Feeding
    Breast Feeding
  • Excreted into milk in small amounts.
  • Should be given cautiously to nursing mother, because of potential adverse effects on infant platelet function.
  • Other Trade Names
     
    The information on this Web site is not intended as a substitute for the advice and care of your doctor or other health-care provider. Always consult your doctor if you have any questions about exposures during pregnancy and lactation, and before you take any medications. Please read the Terms and Conditions before using this website.
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