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Generic Name
Ofloxacin
Trade Name
Oflacin
Manufacturer
Ram Pharma
Risk Category
C
  • Studies on animals show adverse effect and toxicity on fetus.
  • No adequate and well controlled studies done on pregnant women.
  • Drugs should be given only if the potential benefit outweighs the potential risk to the fetus.
FDA Pregnancy Risk Categories

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Indication
Indication
  • anti-infective. Quinolone
  • Fetal Risk
    Fetal Risk
  • fetotoxic in animals at high doses causing decreased fetal weight and increased mortality.
  • Causes minor skeletal malformations in some animals exposed in utero to high doses. In general fluoroquinolones can cause cartilage damage with subsequent arthropathy in animals exposed in utero.
  • Crosses human placenta.
  • Limited human data, but contraindicated in 1st trimester because of possible association with congenital anomalies as: hypospadias, inguinal hernia, maldescensus testis, ureterostenosis, hip dysplasia, myelomeningocele, hydrocephaly and cardiac defects.
  • Possible cause of intrauterine growth retardation and prematurity.
  • Breast Feeding
    Breast Feeding
  • Excreted into milk.
  • No recommended because of potential arthropathy in infants exposed.
  • Phototoxic with excessive exposure to sunlight.
  • Causes squamous cell carcinoma of the skin with exposure to uv light in animals.
  • Other Trade Names
     
    The information on this Web site is not intended as a substitute for the advice and care of your doctor or other health-care provider. Always consult your doctor if you have any questions about exposures during pregnancy and lactation, and before you take any medications. Please read the Terms and Conditions before using this website.
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