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Generic Name
Pentoxifylline (Oxypentifylline)
Trade Name
Oxyphyl
Manufacturer
Hikma
Risk Category
C
  • Studies on animals show adverse effect and toxicity on fetus.
  • No adequate and well controlled studies done on pregnant women.
  • Drugs should be given only if the potential benefit outweighs the potential risk to the fetus.
FDA Pregnancy Risk Categories

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Indication
Indication
  • Blood viscosity reducing agent for treatment of peripheral vascular disease.
  • Fetal Risk
    Fetal Risk
  • fetotoxic in animals at high doses causing fetal resorption .
  • No teratogenic effects have been reported.
  • No adequate human data but suggested possible association with cardiovascular defects and spina bifida in first trimester exposure.
  • Tumerogenic effect in animals has been reported at high doses preducing benign mammary fibroadenomas in females.
  • Breast Feeding
    Breast Feeding
  • Excreted into milk.
  • Breast feeding during therapy is not recommended because of tumorigenic effects demonstrated in animals.
  • Other Trade Names
     
    The information on this Web site is not intended as a substitute for the advice and care of your doctor or other health-care provider. Always consult your doctor if you have any questions about exposures during pregnancy and lactation, and before you take any medications. Please read the Terms and Conditions before using this website.
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