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Generic Name
Procarbazine
Trade Name
Matulane
Risk Category
D
  • Positive evidence of human fetal risk exists.
  • Potential benefits may warrant use of the drug in pregnant women despite potential risks (e.g. life threatening situations or serious illness).
FDA Pregnancy Risk Categories

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Indication
Indication
  • antineoplastic.
  • Fetal Risk
    Fetal Risk
  • teratogenic, toxic in animals when used early in pregnancy. The drug is also mutagenic and carcinogenic in animals.
  • No well controlled human data but reported associated with congenital defects in 1st trimester exposure: hemangiomas, limb defects, cerebral hemorrhage, renal defects intrauterine growth retardation, and cardiac defects.
  • May produce dose-related reversible gonadal dysfunction in males and females.
  • Occupational maternal exposure of pregnant women to antineoplastic agent carries risk to the fetus including fetal loss and malformations.
  • Breast Feeding
    Breast Feeding
  • No data available.
  • Other Trade Names
     
    The information on this Web site is not intended as a substitute for the advice and care of your doctor or other health-care provider. Always consult your doctor if you have any questions about exposures during pregnancy and lactation, and before you take any medications. Please read the Terms and Conditions before using this website.
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