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Generic Name
Propylthiouracil
Trade Name
Propyl-Thyracil
Risk Category
D
  • Positive evidence of human fetal risk exists.
  • Potential benefits may warrant use of the drug in pregnant women despite potential risks (e.g. life threatening situations or serious illness).
FDA Pregnancy Risk Categories

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Indication
Indication
  • Antithyroid for treatment of maternal hyperthyroidism.
  • Fetal Risk
    Fetal Risk
  • Crosses human placenta.
  • No adequate human data in first trimester but reported possible association with congenital malformations including: hypospadias, dislocation of hip, syndactyly, aortic atresia, atresia: Congenital absence or narrowing of gall bladder canal">choanal atresia, muscular hypotonicity and cryptorchidism.
  • Can cause fetal hypothyroidism and goiter.
  • Breast Feeding
    Breast Feeding
  • Excreted into milk in small amounts.
  • Compatible with breast feeding, but infant’s thyroid function should be closely monitored.
  • Other Trade Names
     
    The information on this Web site is not intended as a substitute for the advice and care of your doctor or other health-care provider. Always consult your doctor if you have any questions about exposures during pregnancy and lactation, and before you take any medications. Please read the Terms and Conditions before using this website.
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