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Generic Name
Pyridoxine (VitaminB 6)
Trade Name
Nestrex
Risk Category
A*
  • Adequate and well-controlled studies have failed to demonstrate risk on fetus.
  • Possibility of fetal harm seems appears remote.
The risk category will be C only if used in doses above the RDA.
FDA Pregnancy Risk Categories

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Indication
Indication
  • Vitamin B6.
  • Water-soluble.
  • The recommended dietary allowance (rda) in pregnancy is 2.2 mg.
  • Fetal Risk
    Fetal Risk
  • Crosses the placenta by active transport, fetal and neonatal levels are higher than maternal.
  • Severe vitamin B6 deficiency is teratogenic in animals.
  • Controversial association between pyridoxine deficiency and pregnancy induced hypertension, abnormal glucose tolerance and gestational diabetes, and hyperemesis gravidarm in pregnant women.
  • Suggested association between high doses of Vitamin B6 and congenital malformations mainly phocomelia.
  • Severe pyridoxine deficiency or excess may be a cause of infantile convulsions.
  • Doubtful association between pyridoxine deficiency and low birth weight, low apgar score and small placenta.
  • Breast Feeding
    Breast Feeding
  • Excreted in milk.
  • Pyridoxine deficient diet can cause convulsions in infants.
  • High doses inhibit lactation.
  • RDA in lactation is 2.1 mg.
  • Safe in breast feeding.
  • Other Trade Names
     
    The information on this Web site is not intended as a substitute for the advice and care of your doctor or other health-care provider. Always consult your doctor if you have any questions about exposures during pregnancy and lactation, and before you take any medications. Please read the Terms and Conditions before using this website.
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