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Generic Name
Sulfonamides
Trade Name
Sulfonamides
Risk Category
B*
  • Controlled studies done on animals in reproduction do not indicate risk to the fetus.
  • No adequate and well-controlled studies done on pregnant women.
The risk category will be D only if used near term.
FDA Pregnancy Risk Categories

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Indication
Indication
  • anti-infective.
  • Fetal Risk
    Fetal Risk
  • teratogenic in some animals.
  • Crosses human placenta.
  • No adequate human data but suggested possible association between first trimester exposure to sulfamethoxazole-trimethoprim and cardiovascular defects and exposure to sulfonamides in general and the following anomalies: tracheoesophageal fistula, cataract, oral clefts, urethral obstruction, limb defects, persisitent ductus arteriosus atrophy of the adrenals and benign tumors.
  • If used close to delivery, sulfonamides cause neonatal jaundice, hemolytic anemia and kernicterus.
  • Breast Feeding
    Breast Feeding
  • Excreted into milk in low concentrations.
  • safe in breast feeding but should be avoided in premature infants, infants with hyperbilirubinemia or glucose-6-phosphate dehydrogenase deficiency.
  • Reported diarrhea and skin rash in exposed infants.
  • Other Trade Names
     
    The information on this Web site is not intended as a substitute for the advice and care of your doctor or other health-care provider. Always consult your doctor if you have any questions about exposures during pregnancy and lactation, and before you take any medications. Please read the Terms and Conditions before using this website.
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