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Generic Name
Trade Name
Risk Category
  • Positive evidence of human fetal risk exists.
  • Potential benefits may warrant use of the drug in pregnant women despite potential risks (e.g. life threatening situations or serious illness).
FDA Pregnancy Risk Categories

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  • Non-steroidal anti-estrogen, antineoplastic for treatment of breast cancer.
  • Fetal Risk
    Fetal Risk
  • carcinogenic in animals producing ovarian, testicular tumors and hepatocellular carcinoma; and producing endometrial cancer in humans.
  • Not teratogenic in animals but fetotoxic, causing growth retardation, prematurity, abortions and fetal death.
  • Causes impaired fertility and decreases implantation rate in animals and abnormalities in sexual differentiation of female fetuses including ovaries)">gonadal and genitourinary tract abnormalities (atrophic ovaries and uterus, vaginal adenosis).
  • Limited data in human pregnancy. A case has been reported of ambiguous genitalia in female fetus exposed in the first 20 weeks of gestation and a case of goldenhar’s syndrome (occuloauriculo-vertebral anomaly) in infant exposed to it in utero during the first two trimesters to Tamoxifen.
  • Higher incidence of abortions occurs in pregnancies following chemotherapy with Tamoxifen but successful outcome may result if pregnancy occurs more than two months after Tamoxifen therapy.
  • Offsprings exposed in utero to Tamoxifen require long-term follow-up because of potential carcinogenicity.
  • Breast Feeding
    Breast Feeding
  • Inhibits lactation.
  • Contraindicated during nursing.
  • Other Trade Names
    The information on this Web site is not intended as a substitute for the advice and care of your doctor or other health-care provider. Always consult your doctor if you have any questions about exposures during pregnancy and lactation, and before you take any medications. Please read the Terms and Conditions before using this website.
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