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Generic Name
Chlorambucil
Trade Name
Leukeran
Manufacturer
GlaxoWellcome
Risk Category
D
  • Positive evidence of human fetal risk exists.
  • Potential benefits may warrant use of the drug in pregnant women despite potential risks (e.g. life threatening situations or serious illness).
FDA Pregnancy Risk Categories

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Indication
Indication
  • A systemic antineoplastic agent.
  • Fetal Risk
    Fetal Risk
  • teratogenic in animals causing urinary tract anomalies.
  • Should not be administered during pregnancy especially during the 1st trimester because of urinary and cardiovascular anomalies observed in exposed infants.
  • Occupational exposure of pregnant women to antineoplastic agents carries risk to the fetus including fetal loss and malformations.
  • Breast Feeding
    Breast Feeding
  • Unknown excretion into human breast milk.
  • Breast feeding is contraindicated with chemotherapy due to its potential adverse effects including side effects, mutagenicity and carcinogenicity.
  • Other Trade Names
     
    The information on this Web site is not intended as a substitute for the advice and care of your doctor or other health-care provider. Always consult your doctor if you have any questions about exposures during pregnancy and lactation, and before you take any medications. Please read the Terms and Conditions before using this website.
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