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Generic Name
Azathioprine
Trade Name
Imuran Tab.
Risk Category
D
  • Positive evidence of human fetal risk exists.
  • Potential benefits may warrant use of the drug in pregnant women despite potential risks (e.g. life threatening situations or serious illness).
FDA Pregnancy Risk Categories

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Indication
Indication
  • Immunosuppressant.
  • Used in organ transplant and in inflammatory bowel disease.
  • Fetal Risk
    Fetal Risk
  • teratogenic in some animals producing limb reduction defects.
  • Crosses human placenta.
  • Questionable association with sporadic congenital defects such as cardiovascular, hypospadias, polydactyly, hypothyroidism, cerebral hemorrhage and cerebral palsy. Reported chromosomal aberrations in infants exposed in utero.
  • Causes immunosuppression in newborns exposed in utero.
  • Possible cause of intrauterine growth retardation and congenital cytomegalovirus infection in infants exposed in utero.
  • Breast Feeding
    Breast Feeding
  • Excreted into human breast milk.
  • Not recommended to be used in nursing mothers due to its potential tumorogenic effects in infants.
  • Other Trade Names
     
    The information on this Web site is not intended as a substitute for the advice and care of your doctor or other health-care provider. Always consult your doctor if you have any questions about exposures during pregnancy and lactation, and before you take any medications. Please read the Terms and Conditions before using this website.
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