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Generic Name
Busulfan (Busulphan)
Trade Name
Myleran
Manufacturer
GlaxoWellcome
Risk Category
D
  • Positive evidence of human fetal risk exists.
  • Potential benefits may warrant use of the drug in pregnant women despite potential risks (e.g. life threatening situations or serious illness).
FDA Pregnancy Risk Categories

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Indication
Indication
  • Alkylating antineoplastic agent.
  • Fetal Risk
    Fetal Risk
  • Causes sterility in male and female offspring of exposed animals.
  • Use in human pregnancy in the 1st trimester is a possible cause of multiple anomalies including: a Urinary tract, liver, spleen, lung defects, hypoplasia of ovaries and thyroid gland, eye defects and intrauterine growth retardation.
  • Causes chromosomal damage of unknown significance to the fetus.
  • Occupational exposure of the mother to antineoplastic agents during pregnancy carries risk to fetus including fetal loss and malformations.
  • Breast Feeding
    Breast Feeding
  • Contraindicated during breast feeding because of possible toxic effects on nursing infants.
  • Other Trade Names
     
    The information on this Web site is not intended as a substitute for the advice and care of your doctor or other health-care provider. Always consult your doctor if you have any questions about exposures during pregnancy and lactation, and before you take any medications. Please read the Terms and Conditions before using this website.
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