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Generic Name
Ifosfamide
Trade Name
Holoxann
Manufacturer
Holoxann
Risk Category
D
  • Positive evidence of human fetal risk exists.
  • Potential benefits may warrant use of the drug in pregnant women despite potential risks (e.g. life threatening situations or serious illness).
FDA Pregnancy Risk Categories

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Indication
Indication
  • antineoplastic.
  • Alkylating agent.
  • Fetal Risk
    Fetal Risk
  • carcinogenic in animals causing leomiyosarcomas and mammary fibroadenomas in females.
  • Teratogenic in animals.
  • No adequate human data, it is contraindicated in pregnancy and mainly in first trimester. Effective contraception should be given during and at least 6 months after administration of cytotoxic drugs.
  • Breast Feeding
    Breast Feeding
  • Excreted into milk.
  • Contraindicated in breast feeding.
  • Breast feeding should be discontinued during therapy because of potential risks to nursing infants.
  • Other Trade Names
     
    The information on this Web site is not intended as a substitute for the advice and care of your doctor or other health-care provider. Always consult your doctor if you have any questions about exposures during pregnancy and lactation, and before you take any medications. Please read the Terms and Conditions before using this website.
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