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Generic Name
Isoflurane
Trade Name
Aerrane
Manufacturer
Zeneca
Risk Category
C
  • Studies on animals show adverse effect and toxicity on fetus.
  • No adequate and well controlled studies done on pregnant women.
  • Drugs should be given only if the potential benefit outweighs the potential risk to the fetus.
FDA Pregnancy Risk Categories

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Indication
Indication
  • General anesthetic.
  • Volatile inhalational anesthetic.
  • Fetal Risk
    Fetal Risk
  • May cause maternal hypotension, tachycardia arrhythmias, respiratory depression and liver toxicity.
  • It is used only in cesarean section and it may suppress neonatal respiration.
  • Use in the first trimester was associated with increased risk of uterine bleeding.
  • Breast Feeding
    Breast Feeding
  • Unknown excretion in breast milk, lactation should be stopped for 12 hours after termination of anesthesia.
  • No problems have been documented in humans.
  • Other Trade Names
     
    The information on this Web site is not intended as a substitute for the advice and care of your doctor or other health-care provider. Always consult your doctor if you have any questions about exposures during pregnancy and lactation, and before you take any medications. Please read the Terms and Conditions before using this website.
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