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Generic Name
Alendronate monosodium
Trade Name
Fosamax
Manufacturer
MSD
Risk Category
C
  • Studies on animals show adverse effect and toxicity on fetus.
  • No adequate and well controlled studies done on pregnant women.
  • Drugs should be given only if the potential benefit outweighs the potential risk to the fetus.
FDA Pregnancy Risk Categories

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Indication
Indication
  • Bisphosphonate.
  • Bone resorption inhibitor.
  • Fetal Risk
    Fetal Risk
  • In animals, it has been shown to cause decreased post-implantation survival and body weight gain of offspring.
  • High doses cause maternal hypocalcemia resulting in delayed parturition, maternal and neonatal deaths.
  • Breast Feeding
    Breast Feeding
  • It is not known whether Alendronate is excreted in human milk.
  • Because many drugs are excreted in human milk, caution should be exercised when Alendronate sodium is administered to nursing women.
  • Other Trade Names
     
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