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Generic Name
Quetiapine
Trade Name
Seroquel
Manufacturer
Zeneca
Risk Category
C
  • Studies on animals show adverse effect and toxicity on fetus.
  • No adequate and well controlled studies done on pregnant women.
  • Drugs should be given only if the potential benefit outweighs the potential risk to the fetus.
FDA Pregnancy Risk Categories

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Indication
Indication
  • Antipsychotic for treatment of schizophrenia.
  • Fetal Risk
    Fetal Risk
  • carcinogenic in animals increasing the incidence of mammary adenocarcinomas in females and thyroid follicular cell benign adenomas in males.
  • By increasing serum prolactin level it impairs fertility and reduces pregnancy rate (in animal studies).
  • Not teratogenic in animals but fetotoxic causing reduced fetal body weight, delayed skeletal ossification.
  • High doses in animals cause reduced weight gain, increased maternal, fetal and postnatal deaths.
  • No adequate human data.
  • Breast Feeding
    Breast Feeding
  • Excreted into milk of lactating animals.
  • Unknown in human but breast feeding is not recommended during therapy.
  • Other Trade Names
     
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