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Generic Name
Silver sulphadiazine
Trade Name
Thermazene
Risk Category
B*
  • Controlled studies done on animals in reproduction do not indicate risk to the fetus.
  • No adequate and well-controlled studies done on pregnant women.
The risk category will be D only if used near term.
FDA Pregnancy Risk Categories

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Indication
Indication
  • The risk factor is D if used near term.
  • Topical antibacterial.
  • Sulphonamide group.
  • Fetal Risk
    Fetal Risk
  • Sulfonamides are teratogenic in animals.
  • Systemic sulphonamide crosses human placenta and if used in the first trimester they are possible cause of increased incidence of multiple congenital anomalies and if used in third trimester close to delivery they nay cause neonatal jaundice and kernicterus.
  • No data about topical application of sulphonamides.
  • Breast Feeding
    Breast Feeding
  • Sulphonamides are excreted into milk in low concentration, they may cause diarrhea and skin rash in exposed infants.
  • They should be avoided in premature infants, infants with hyperbilirubinemia or glucose -6-phosphate dehydrogenase deficiency.
  • No data about topical sulphonamides.
  • Other Trade Names
     
    The information on this Web site is not intended as a substitute for the advice and care of your doctor or other health-care provider. Always consult your doctor if you have any questions about exposures during pregnancy and lactation, and before you take any medications. Please read the Terms and Conditions before using this website.
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