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Generic Name
Tacrolimus
Trade Name
Tacrolimus
Risk Category
C
  • Studies on animals show adverse effect and toxicity on fetus.
  • No adequate and well controlled studies done on pregnant women.
  • Drugs should be given only if the potential benefit outweighs the potential risk to the fetus.
FDA Pregnancy Risk Categories

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Indication
Indication
  • Immunosuppressant for prevention of graft rejection.
  • Fetal Risk
    Fetal Risk
  • fetotoxic in animals causing increased late fetal loss and decreased live birth rate.
  • Crosses human placenta.
  • No adequate human studies, but reported to cause preterm delivery, intrauterine growth retardation (single case), hyperkalemia and reversible renal impairment in the neonates.
  • Breast Feeding
    Breast Feeding
  • Excreted into milk.
  • Breastfeeding should be discontinued during therapy.
  • Other Trade Names
     
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