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Generic Name
Daunorubicin Hydrochloride
Trade Name
Daunoblastina
Manufacturer
Pharmacia & uupjhon
Risk Category
D
  • Positive evidence of human fetal risk exists.
  • Potential benefits may warrant use of the drug in pregnant women despite potential risks (e.g. life threatening situations or serious illness).
FDA Pregnancy Risk Categories

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Indication
Indication
  • Anti-neoplastic.
  • Fetal Risk
    Fetal Risk
  • No well controlled human data but reported assocaition between daunorubicin exposure in pregnancy and neonatal electrolyte imbalance, hypoglycemia, myelosuppression, intrauterine growth retardation, intrauterine death with myocardial necrosis.
  • Doubtful association between paternal use of the drug and congenital anomalies in their offsprings including: anencephaly, tetralogy of fallot and syndactyly.
  • May cause chromosomal aberrations in children exposed in utero producing chromosomal gaps and rings with subsequent risk of cancer and genetic damage in the next generation.
  • Occupational exposure of the mother to antineoplastic agents during pregnancy carries risk to the fetus, increasing fetal loss and anomalies.
  • Breast Feeding
    Breast Feeding
  • Use by nursing mothers is not recommended because of adverse effects on the infant, mutagenicity and carcinogenicity.
  • Other Trade Names
     
    The information on this Web site is not intended as a substitute for the advice and care of your doctor or other health-care provider. Always consult your doctor if you have any questions about exposures during pregnancy and lactation, and before you take any medications. Please read the Terms and Conditions before using this website.
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