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Generic Name
Candesartan Cilexitil
Trade Name
Amias
Manufacturer
(AstraZeneca) (Takeda)
Risk Category
D*
  • Positive evidence of human fetal risk exists.
  • Potential benefits may warrant use of the drug in pregnant women despite potential risks (e.g. life threatening situations or serious illness).
The risk category is C in the first trimester.
FDA Pregnancy Risk Categories

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Indication
Indication
  • Angiotensin II receptor antagonist for treatment of hypertension.
  • Fetal Risk
    Fetal Risk
  • In animals it causes late fetal and neonatal injury in the kidney.
  • No human experience with its use in pregnancy but in general, use of angiotensin II antagonists during the last two trimesters of pregnancy is associated with: intrauterine growth retardation, renal tubular dysplasia leading to neonatal anuria and renal failure, oligohydramnios leading to skull and limb deformalities and lung hypoplasia.
  • Breast Feeding
    Breast Feeding
  • Excreted into milk in animals.
  • Unknown excretion into human milk.
  • Not recommended during breast feeding.
  • Other Trade Names
     
    The information on this Web site is not intended as a substitute for the advice and care of your doctor or other health-care provider. Always consult your doctor if you have any questions about exposures during pregnancy and lactation, and before you take any medications. Please read the Terms and Conditions before using this website.
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