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Generic Name
Timolol Maleate
Trade Name
Timoptol
Manufacturer
MSD
Risk Category
C
  • Studies on animals show adverse effect and toxicity on fetus.
  • No adequate and well controlled studies done on pregnant women.
  • Drugs should be given only if the potential benefit outweighs the potential risk to the fetus.
FDA Pregnancy Risk Categories

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Indication
Indication
  • Non-selective beta-adrenergic blocking agent for treatment of hypertension, for proplylaxis of migraine headache, after myocardial infarction and topically for treatment of glaucoma.
  • Fetal Risk
    Fetal Risk
  • Not teratogenic but fetotoxic in animals.
  • Crosses human placenta.
  • Limited human data for timolol but other beta-blockers can cause intrauterine growth retardation if used in second and third trimesters and persistent neonatal beta-blockade if used near term.
  • Breast Feeding
    Breast Feeding
  • Excreted into milk.
  • Compatible with breast feeding but infant should be closely observed for symptoms of beta-blockade.
  • Unknown long-term effects on nursing infants.
  • Other Trade Names
     
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