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Generic Name
Tobramycin Sulphate
Trade Name
Eli Lilly
Risk Category
  • Positive evidence of human fetal risk exists.
  • Potential benefits may warrant use of the drug in pregnant women despite potential risks (e.g. life threatening situations or serious illness).
FDA Pregnancy Risk Categories

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  • Aminoglycoside antibiotic.
  • Fetal Risk
    Fetal Risk
  • The drug is not teratogenic in animals but it causes fetal renal toxicity if used at high doses during organogenesis.
  • Crosses human placenta.
  • No adequate human data but possible association with cardiovascular anomalies in 1st trimester exposure.
  • Use of other aminoglycosides in pregnancy (see kenamycin and treptamycin0 resulted in fetal eighth cranial nerve toxicity. The data is lacking for tobramycine.
  • Breast Feeding
    Breast Feeding
  • Excreted into milk.
  • Oral absorption in poor.
  • Potential problems for nursing infants including change in bowel flora, and direct effects of the drug.
  • Other Trade Names
    The information on this Web site is not intended as a substitute for the advice and care of your doctor or other health-care provider. Always consult your doctor if you have any questions about exposures during pregnancy and lactation, and before you take any medications. Please read the Terms and Conditions before using this website.
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