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Generic Name
Trade Name
Risk Category
  • Positive evidence of human fetal risk exists.
  • Potential benefits may warrant use of the drug in pregnant women despite potential risks (e.g. life threatening situations or serious illness).
FDA Pregnancy Risk Categories

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  • A systemic antineoplastic agent used in the treatment of breast and colorectal carcinomas.
  • Fetal Risk
    Fetal Risk
  • No adequate human data but suggested possible association between systemic use of the drug in first trimester and multiple congenital anomalies including: limb, digital, vascular, gestrointestinal and urinary defects, single umbilical artery.
  • No data about topical use of the drug.
  • Reported neonatal toxic effects when the drug used in third trimester including cyanosis and jerking extremities.
  • Occupational exposure of pregnant women to antineoplastic drugs carries risk to the fetus including fetal loss and malformations.
  • Breast Feeding
    Breast Feeding
  • Unknown excretion into human breast milk.
  • Not recommended for use in nursing mothers due to potential risks to the neonate.
  • Other Trade Names
    The information on this Web site is not intended as a substitute for the advice and care of your doctor or other health-care provider. Always consult your doctor if you have any questions about exposures during pregnancy and lactation, and before you take any medications. Please read the Terms and Conditions before using this website.
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